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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCLK1 All Species: 26.06
Human Site: S307 Identified Species: 52.12
UniProt: O15075 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15075 NP_004725.1 740 82224 S307 G P S R R S K S P A S T S S V
Chimpanzee Pan troglodytes XP_522657 872 96662 S450 G P S R R S K S P A S T S S V
Rhesus Macaque Macaca mulatta XP_001082020 783 85228 S328 V K R G G H Y S S A Y S T A K
Dog Lupus familis XP_849124 740 82175 S307 G P S R R S K S P A S T S S V
Cat Felis silvestris
Mouse Mus musculus Q9JLM8 756 84135 S307 G P S R R S K S P A S T S S V
Rat Rattus norvegicus Q5MPA9 767 83998 S326 S V K R A G H S S A Y S T A K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511397 792 88039 S368 G P S R R S K S P A S T S S V
Chicken Gallus gallus XP_417099 1048 115422 S613 G P S R R S K S P A S T S S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q501V0 422 47914 V16 L P E P P G D V Q L D L V K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLI7 748 82953 N294 A C G G G T G N G S P L I A S
Honey Bee Apis mellifera XP_394386 670 74883 F263 Q E D F E L D F E E S K S V Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189418 661 74296 F255 F F K D D D V F I A Y G Q E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.4 65.3 99.8 N.A. 96.4 65.3 N.A. 86.2 63.7 N.A. 24.7 N.A. 29.8 41 N.A. 52.3
Protein Similarity: 100 80.1 77.5 99.8 N.A. 97.3 77.8 N.A. 88 64.9 N.A. 35 N.A. 47.5 57.9 N.A. 65.9
P-Site Identity: 100 100 13.3 100 N.A. 100 20 N.A. 100 100 N.A. 6.6 N.A. 0 13.3 N.A. 6.6
P-Site Similarity: 100 100 33.3 100 N.A. 100 40 N.A. 100 100 N.A. 6.6 N.A. 26.6 13.3 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 0 0 0 75 0 0 0 25 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 9 9 9 17 0 0 0 9 0 0 0 0 % D
% Glu: 0 9 9 0 9 0 0 0 9 9 0 0 0 9 0 % E
% Phe: 9 9 0 9 0 0 0 17 0 0 0 0 0 0 0 % F
% Gly: 50 0 9 17 17 17 9 0 9 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % I
% Lys: 0 9 17 0 0 0 50 0 0 0 0 9 0 9 25 % K
% Leu: 9 0 0 0 0 9 0 0 0 9 0 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % N
% Pro: 0 59 0 9 9 0 0 0 50 0 9 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 9 0 0 0 9 0 9 % Q
% Arg: 0 0 9 59 50 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 9 0 50 0 0 50 0 67 17 9 59 17 59 50 9 % S
% Thr: 0 0 0 0 0 9 0 0 0 0 0 50 17 0 0 % T
% Val: 9 9 0 0 0 0 9 9 0 0 0 0 9 9 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 25 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _